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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Hepatology. 2020 Oct 30;73(2):571–585. doi: 10.1002/hep.31256

TABLE 1.

Circulating EV Counts

EV concentration (particles/ml) Healthy Controls Heavy Drinkers NASH PBC and PSC Decompensated Alcoholic Cirrhosis Alcoholic Hepatitis
Minimum 2.8 × 109 1.25 × 1010 1.08 × 1010 1.8 × 1010 1.6 × 1010 7.65 × 1010
25th Percentile 1.91 × 1010 8.94 × 1010 2.6 × 1010 2.9 × 1010 5.18 × 1010 2.75 × 1011
Median 4.38 × 1010 1.28 × 1011 3.06 × 1010 6.29 × 1010 9.2 × 1010 5.38 × 1011
75th Percentile 8.88 × 1010 1.91 × 1011 5.74 × 1010 1.18 × 1011 1.53 × 1011 1.01 × 1012
Maximum 3.63 × 1011 4.68 × 1011 1.76 × 1011 1.98 × 1011 1.1 × 1012 2.5 × 1012

Statistical comparisons of EV counts: AH vs. healthy controls (p<0.0001), AH vs. heavy drinkers (p=0.0001), AH vs. NASH and cholestatic liver diseases (p<0.0001), AH vs. decompensated alcoholic cirrhosis (p<0.0001).