TABLE 1.
Circulating EV Counts
EV concentration (particles/ml) | Healthy Controls | Heavy Drinkers | NASH | PBC and PSC | Decompensated Alcoholic Cirrhosis | Alcoholic Hepatitis |
---|---|---|---|---|---|---|
Minimum | 2.8 × 109 | 1.25 × 1010 | 1.08 × 1010 | 1.8 × 1010 | 1.6 × 1010 | 7.65 × 1010 |
25th Percentile | 1.91 × 1010 | 8.94 × 1010 | 2.6 × 1010 | 2.9 × 1010 | 5.18 × 1010 | 2.75 × 1011 |
Median | 4.38 × 1010 | 1.28 × 1011 | 3.06 × 1010 | 6.29 × 1010 | 9.2 × 1010 | 5.38 × 1011 |
75th Percentile | 8.88 × 1010 | 1.91 × 1011 | 5.74 × 1010 | 1.18 × 1011 | 1.53 × 1011 | 1.01 × 1012 |
Maximum | 3.63 × 1011 | 4.68 × 1011 | 1.76 × 1011 | 1.98 × 1011 | 1.1 × 1012 | 2.5 × 1012 |
Statistical comparisons of EV counts: AH vs. healthy controls (p<0.0001), AH vs. heavy drinkers (p=0.0001), AH vs. NASH and cholestatic liver diseases (p<0.0001), AH vs. decompensated alcoholic cirrhosis (p<0.0001).