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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Comp Neurol. 2020 Jun 27;528(17):2864–2873. doi: 10.1002/cne.24957

Figure 4.

Figure 4.

Interocular differences in BMP2, BMP4 and BMP7 gene expression in RPE after 2 and 48 h of −10 D lens wear: (A) graph showing these differences as mean ratios of expression (T/C), expressed as percentages ± SEMs, and (B) cartoon heat maps of the same; mRNA levels normalized to GADPH for treated and control eyes and 3 RPE zones: (C) BMP2, (D) BMP4, and (E) BMP7. For the BMP2 gene, expression significantly decreased in treated compared to control eyes in all three RPE zones after 2 h treatment, as well as in zones 3 and 6 after 48 h treatment; significantly decreased expression after 2 h of treatment limited to zone 3 for BMP4 and to zone 6 for BMP7. * p < 0.05, ** p < 0.01.