Table 3.

Fine and Gray Subdistribution Hazard of Cause-Specific Mortality by Coronary Artery Calcium Score and Age

	CAC = 0	CAC 1–99	CAC 100–399	CAC ≥ 400
Coronary heart disease
40–54 years	Reference	2.44(1.25–4.76)	4.48 (2.06–9.72)	11.78 (5.58–24.87)
55–64 years	Reference	1.40 (0.74–2.67)	2.48 (1.28–4.78)	6.12 (3.32–11.29)
65–75 years	Reference	0.94 (0.43–2.06)	2.68 (1.31–5.50)	3.76 (1.84–7.68)
Overall	Reference	1.59 (1.06–2.39)	3.35 (2.19–2.40)	5.69 (3.78–8.58)
Cardiovascular disease
40–54 years	Reference	1.55 (1.00–2.40)	2.80 (1.64–4.77)	5.90 (3.37–10.32)
55–64 years	Reference	1.66 (1.06–2.59)	2.94 (1.84–4.67)	5.70 (3.60–9.02)
65–75 years	Reference	1.22 (0.75–2.00)	2.06 (1.27–3.33)	3.12 (1.93–5.02)
Overall	Reference	1.50 (1.15–1.95)	2.59 (1.96–3.42)	4.46 (3.36–5.93)
Noncardiovascular disease
40–54 years	Reference	1.25 (0.99–1.58)	1.64 (1.17–2.29)	2.40 (1.62–3.53)
55–64 years	Reference	1.22 (0.98–1.52)	1.44 (1.12–1.84)	2.09 (1.63–2.67)
65–75 years	Reference	1.10 (0.86–1.42)	1.27 (0.98–1.64)	1.56 (1.20–2.01)
Overall	Reference	1.20 (1.05–1.37)	1.43 (1.23–1.66)	1.90 (1.62–2.22)
Cancer
Age 40–54	Reference	1.06 (0.75–1.48)	1.21 (0.81–2.02)	1.00 (0.48–2.10)
Age 55–64	Reference	1.00 (0.76–1.31)	1.19 (0.87–1.61)	1.58 (1.16–2.16)
Age 65–75	Reference	1.02 (0.73–1.41)	1.03 (0.73–1.44)	1.07 (0.75–1.51)
Overall	Reference	1.03 (0.87–1.23)	1.15 (0.94–1.41)	1.32 (1.07–1.64)

CAC = coronary artery calcium.

^*Adjusted for age, gender, hypertension, hyperlipidemia, smoking, diabetes, and family history of coronary heart disease.