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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2020 Jul 22;29(10):1983–1992. doi: 10.1158/1055-9965.EPI-20-0248

Figure 1. The region ch13q22.2 (represented by rs12875562) and lung adenocarcinoma survival.

Figure 1.

(a) Forest plots for study-specific hazard ratios (HR) and 95% confidence intervals (CI)

(b) Kaplan-Meier plot by genotype of the sentinel variant over 5-year time period.

(c) Regional plot that include the 1Mb around the sentinel variant rs12875562. X-axis represent the chromosome position and Y-axis represent –log10 (p-value) with color representing the linkage disequilibrium with the sentinel variant in r2

(d) eQTL p-value from the GTEx data based on normal lung tissues

(e) eQTL P-values from the Lung eQTL dataset: Laval University, University of British Columbia (UBC) and University of Groningen. The left y axis represents gene expression levels in the lung adjusted for age, sex and smoking status. The x axis represents genotyping groups for rs12875562.