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. 2020 Oct 7;10:118. doi: 10.1186/s13550-020-00704-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Curve fitting for the compartment analysis and correlation analysis with V_T. a Quality of curve fitting for a representative hepatic time-activity curve and b correlation between V_T obtained using IDIF and V_T obtained using AIF. Saline or unlabelled RGD (0.1, 0.3, 1, or 3 mg/kg) were administered intravenously 5 min before ¹⁸F-FPP-RGD₂. 1T2C model one-tissue two-compartment model, 2T3C model two-tissue three-compartment model, IDIF image-derived input function, AIF arterial input function