Table 3.

Kinetic parameters, determined using compartment analysis

Group	Model	K1	k2	k3	k4	AIC
3–4 weeks
Normal diet	1T2CM	1.06 ± 0.26	2.08 ± 0.40	–	–	89.33 ± 4.8
	2T3CM	1.43 ± 0.34	3.63 ± 0.87	0.05 ± 0.012	0.03 ± 0.0063	35.96 ± 3.8
CDHFD	1T2CM	0.74 ± 0.14	1.15 ± 0.32	–	–	93.31 ± 10.7
	2T3CM	0.90 ± 0.12	1.94 ± 0.47	0.05 ± 0.020	0.02 ± 0.0021	41.14 ± 3.9
9–10 weeks
Normal diet	1T2CM	0.87 ± 0.34	1.56 ± 0.85	–	–	97.59 ± 3.8
	2T3CM	1.26 ± 0.14	3.00 ± 0.40	0.05 ± 0.0075	0.02 ± 0.0048	43.93 ± 5.9
CDHFD	1T2CM	0.42 ± 0.26	0.51 ± 0.61	–	–	100.3 ± 7.9
	2T3CM	0.69 ± 0.14	1.19 ± 0.39	0.07 ± 0.0079	0.02 ± 0.0029	32.12 ± 7.8

Values are expressed as means ± SDs (n = 5)

CDHFD choline-deficient, low-methionine high-fat diet, 1T2CM one-tissue two-compartment model, 2T3CM two-tissue three-compartment model, AIC Akaike information criterion