TABLE 1.
Basic and clinical patient characteristics.
|
(A) LPL donors | ||||
| Characteristics | HD | CD | UC | IC |
| n | 30 | 13 | 15 | 1 |
| Female/male | 16/14 | 7/6 | 9/6 | 0/1 |
| Median age at sampling (RANGE) | 61.3 (34–90) | 38.38 (23–58) | 45.67 (21–66) | 31 |
| Disease specific medication | ||||
| Mesalazine | - | 5 | 14 | 1 |
| Azathioprine | - | 2 | 2 | 1 |
| Corticosteroids | - | 1 | 2 | - |
| Mercaptopurine | - | 1 | - | |
| Anti-TNF-α | - | 3 | 1 | - |
| Anti-IL-12 + Anti-IL-23 | - | 2 | - | - |
| Anti-α4β7 | - | 1 | 1 | - |
| (B) PBMC donors | ||||
| Characteristics | HD | CD | UC | |
| n | 9 | 5 | 5 | |
| Female/male | 5/4 | 2/3 | 1/4 | |
| Median age at sampling (RANGE) | 25,33 (23-29) | 48 (28-69) | 38,4 (27-54) | |
| Disease specific medication | ||||
| Mesalazine | - | - | 2 | |
| Azathioprine | - | 1 | 1 | |
| Corticosteroids | - | 2 | 3 | |
| Anti-α4β7 | - | 3 | 1 | |
| Anti-TNF-α | - | 1 | - | |
HD, healthy donors; CD, Crohn‘s disease; UC, ulcerative colitis; IC, indeterminate colitis; LPL, lamina propria lymphocytes; PBMC, peripheral blood mononuclear cells.