TABLE 3.

DESeq2 analysis of the operational taxonomic units (OTUs) that showed the most significant (A) increase, or (B) decrease, in abundance from the end of the first consecutive batch culture (CBC1) to the end of the last (CBC9) of Experiment 1.

(A)		Increased from CBC1 to CBC 9
		Genus	Fold changea	P-valueb
	OTU 11	Bacteroidales UCG-001 unclassified	10.0	< 0.001
	OTU 24	Ruminococcus 1	9.67	< 0.001
	OTU 19	Bacteroidales S24-7 group unclassified	9.30	< 0.001
	OTU 15	Streptococcus	7.46	0.002
	OTU 42	Escherichia-Shigella	8.56	0.002
	OTU 60	Pyramidobacter	8.37	0.002
	OTU 76	Prevotella 1	8.53	0.002
	OTU 38	Prevotella 1	7.88	0.003
	OTU 49	Bacteroidales UCG-001 unclassified	8.42	0.003
	OTU 7	Ruminococcus 1	7.51	0.004
(B)		Decreased from CBC1 to CBC 9
		Genus	Fold changea	P-valueb
	OTU 27	Fibrobacter	–11.6	< 0.001
	OTU 64	Fibrobacter	–9.51	< 0.001
	OTU 170	Prevotella 1	–8.90	0.002
	OTU 18	Fibrobacter	–6.78	0.002
	OTU 139	Bacteroidales UCG-001 unclassified	–8.42	0.002
	OTU 149	Treponema 2	–8.81	0.002
	OTU 166	Ruminococcaceae NK4A214 group	–8.65	0.002
	OTU 176	Bacteroidales S24-7 group unclassified	–8.60	0.002
	OTU 219	Prevotella 7	–8.49	0.002
	OTU 112	Fibrobacter	–7.70	0.003

^aLog2 fold change ^bP-values shown are corrected for multiple testing using the Benjamin-Hochberg correction.