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. 2020 Sep 24;10:559896. doi: 10.3389/fonc.2020.559896

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Copyright © 2020 Xiang, Fu, Wang, Li, Zheng, Nan and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation between KRAS mutational status and copy number alteration burden. (A) Patients with KRAS concurrent mutations have greater copy number alteration burden with only KRAS mutation. (B) Comparison of copy number alteration burden in KRAS co-mutation subtypes. (C,D) Comparison of copy number alteration burden in KRAS G12C (C) or G > T (D) subtypes with concurrent mutations. MUT, mutant; WT, wild-type. Box plot data are presented as mean, interquartile ranges, and ranges. ***P < 0.001; **P < 0.01.