TABLE 1.

Univariable and multivariable Cox proportional hazards regression.

	Univariable analysis				Multivariable analysis
		95%CI				95%CI
Variable	HR	Lower	Upper	P	HR	Lower	Upper	P
Age	1.00	0.99	1.01	0.942
Gender (male vs. female)	1.04	0.76	1.42	0.809
Smoker (yes vs. no)	0.74	0.51	1.06	0.103
TMB (≥13.27 mut/Mb vs. <13.27 mut/Mb)	0.54	0.34	0.85	0.008	0.46	0.29	0.73	0.0011
CNA (≥0.05 vs. <0.05)	1.63	1.15	2.31	0.007	1.86	1.30	2.66	0.0007

HR, hazard ratio; CI, confidence interval.