Table 2. Comparison of MS lesions with and without paramagnetic rims.
| MS lesions with paramagnetic rims | MS lesions without paramagnetic rims | p | |
|---|---|---|---|
| Number of patients | 27 | 5 | - |
| Sex, male:female | 5:22 | 2:3 | 0.632 |
| Age, years | 30.0 [24.9–41.6] | 40.5 [35.5–54.4] | 0.098 |
| Disease duration at first MRI scan, months | 29.9 [1.3–63.6] | 54.4 [47.3–66.2] | 0.161 |
| EDSS score at first MRI | 1.5 [1.0–2.2] | 2.0 [1.0–2.5] | 0.832 |
| Per-patient analysis | |||
| Number of T2-weighted lesions | 12 [7–16] | 5 [5–12] | 0.076 |
| 13.0±9.0 | 8.0±5.2 | 0.240 | |
| Contrast-enhanced lesions | 9/27 (33.3) | 2/5 (40.0) | 1.000 |
| Per-MRI analysis | |||
| Number of MRI scans | 58 | 13 | |
| Age, years | 29.9 [24.8–39.7] | 40.5 [27.4–54.4] | 0.071 |
| Disease duration, months | 33.1 [7.2–67.9] | 49.9 [25.9–62.0] | 0.624 |
| Disease-modifying therapy | 42 (72.4) | 8 (61.5) | 0.660 |
| MRI scans in the acute phase of clinical attacks* | 7 (12.1) | 3 (23.1) | 0.555 |
Data are mean±standard deviation, n (%), or median [interquartile range] values.
*Attacks in any location of the central nervous system, including the brain, optic nerve, or spinal cord.
EDSS: Expanded Disability Status Scale, MRI: magnetic resonance imaging, MS: multiple sclerosis.