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. 2020 Sep 9;16(4):562–572. doi: 10.3988/jcn.2020.16.4.562

Table 3. Comparison of follow-up MRI scans in MS and NMOSD patients.

MS NMOSD p
Number of patients 22 10 -
Sex, male:female 5:17 0:10 0.264
Age, years 33.2±9.5 51.8±13.7 <0.001
Disease duration to first MRI scan, months 30.9 [4.3–54.4] 30.2 [0.4–185.2] 0.617
Disease duration to last MRI scan, months 42.3 [13.0–66.9] 37.9 [13.4–197.7] 0.675
Follow-up duration, months 15.8 [10.7–26.4] 14.2 [9.7–16.6] 0.204
EDSS score 1.2 [1.0–2.5] 3.0 [1.5–3.5] 0.029
Per-patient analysis
 New T2-weighted lesions 12/22 (54.5) 5/10 (50.0) 1.000
 New lesions with paramagnetic rims 8/22 (36.4) 1/10 (10.0) 0.266
 New contrast-enhanced lesions 5/22 (22.7) 3/10 (30.0) 1.000
 Number of lesions 12 [6–16] 8 [3–19] 0.554
 Numbers of lesions with paramagnetic rims 3.5 [1–8] 0 [0–0] 0.002
Per-lesion analysis
 Number of lesions at last MRI scan 282 105
 New T2-weighted lesions 33 (11.7) 33 (31.4) <0.001
 New paramagnetic rims 19 (6.7) 19 (18.1) 0.002

Data are mean±standard deviation, n (%), or median [interquartile range] values.

EDSS: Expanded Disability Status Scale, MRI: magnetic resonance imaging, MS: multiple sclerosis, NMOSD: neuromyelitis optica spectrum disorder.