TABLE 1.

Descriptive statistics for 33 plasma metabolites: number of animals per metabolite (n), mean, standard deviation (SD), coefficient of variation (CV), minimum (Min.) and maximum (Max.).

Trait	n	Mean	SD	CV	Min.	Max.
1-Methylhistidine	435	56.26	22.71	0.40	15.34	136.31
2-Hydroxybutyrate	460	41.23	17.02	0.41	12.26	94.48
Acetic acid	462	264.60	256.05	0.97	33.40	2,056.21
Betaine	448	111.67	52.97	0.47	29.62	298.33
Creatine	451	127.59	44.39	0.35	41.98	262.67
Citric acid	448	120.27	65.38	0.54	15.61	338.45
Choline	456	346.37	173.98	0.50	61.35	960.08
Ethanol	404	61.38	84.91	1.38	13.53	560.94
D-Glucose	452	837.40	692.11	0.83	68.42	3,731.80
Glycine	451	378.65	162.32	0.43	90.38	896.70
Glycerol	452	511.10	354.71	0.69	15.68	1,532.64
Fumaric acid	300	23.85	8.48	0.36	10.75	66.11
Formic acid	454	30.34	28.25	0.93	9.46	370.87
L-Tyrosine	475	65.51	19.32	0.29	22.88	119.90
L-Phenylalanine	454	67.54	19.54	0.29	27.53	125.61
L-Alanine	446	390.34	148.99	0.38	104.46	852.47
L-Proline	465	129.58	41.02	0.32	42.09	257.82
L-Isoleucine	465	52.85	19.88	0.38	15.11	120.63
L-Histidine	450	76.09	28.57	0.38	23.35	150.45
Lysine	460	70.34	26.19	0.37	15.24	154.49
L-Lactic acid	450	5,024.04	2,790.01	0.56	885.17	15,976.05
Pyruvic acid	321	87.56	81.42	0.93	14.23	395.75
Succinic acid	448	58.47	34.46	0.59	14.86	280.58
3-Hydroxybutyric acid	457	86.65	41.66	0.48	18.29	272.70
Creatinine	451	132.14	57.85	0.44	30.77	308.61
L-Glutamine	441	58.97	23.00	0.39	14.35	119.97
L-Leucine	475	93.08	39.48	0.42	25.63	302.17
L-Methionine	193	20.72	4.49	0.22	12.08	33.77
3-Hydroxyisovaleric acid	155	32.38	13.02	0.40	11.70	79.06
L-Valine	454	147.16	49.58	0.34	49.88	313.97
Acetone	260	35.97	19.84	0.55	12.47	125.08
Methanol	447	135.47	76.28	0.56	31.35	383.19
Dimethyl sulfone	449	46.86	19.41	0.41	15.31	128.60

Unit:μM.