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. 2020 Oct 7;11(10):832. doi: 10.1038/s41419-020-2584-z

Fig. 6. LL22NC03-N14H11.1 regulated HCC progression and mitochondrial fission through LZTR1/H-RAS (G12V).

Fig. 6

ae HCC cells were transfected with sh-NC (a), sh-LL22NC03-N14H11.1#1 (b), sh-LL22NC03-N14H11.1#1 + sh-LZTR1 (c), or sh-LL22NC03-N14H11.1#1 + H-RAS (G12V) (d), respectively. Proliferation, apoptosis, invasion, and migration of HCC cells were evaluated by CCK-8, colony formation, transwell invasion, and wound healing assays, respectively. f Western blot analysis of E-cadherin, N-cadherin, MMP2, and MMP7 in HCC cells of each group. g MitoTracker Red staining and quantification of mitochondrial fission in HCC cells of each group. Scale bar: 3 μm. **P < 0.01.