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. 2020 Oct 7;10:16756. doi: 10.1038/s41598-020-73802-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cell-deposition of fibronectin. Chronic isoproterenol (ISO) treatment (1 µM) for 7 days for both MFS and corrected cell cultures is compared with no treatment using immunohistochemistry staining for cTnT and fibronectin, nuclei visualised with HOECHST. Bar indicates 100 µm. Bar graphs show average fluorescent intensity of cTnT and fibronectin for corrected (n = 3, black) and MFS (n = 3, red) with ISO treatment and no treatment. The level of significance is indicated by asterisks: p values less than 0.05 are indicated with one asterisk.