FIGURE 1.

Cluster analysis of CGRP⁺ and IB4⁺ neurons in DRGs from control and diabetic mice. Representative pictures of CGRP⁺ (a) and IB4⁺ (b) neurons in DRGs from CTR. The enlargements below illustrate the diameters of representative CGRP⁺ and IB4⁺ cells. (c) Histogram showing the number of cells per cluster of CGRP⁺ and IB4⁺ neurons in vehicle‐treated (IB4⁺ n = 48; CGRP, n = 58; t‐test, p < .001) and STZ‐treated mice (IB4⁺ n = 57; CGRP, n = 56; t‐test, p < .001). CGRP, calcitonin gene‐related peptide; CTR, vehicle‐treated mice; IB4, isolectin B4; STZ, streptozotocin‐treated mice. ****p < .0001