Table 4.
Number of significant CpG targets hypermethylation | Number of significant CpG targets hypomethylation | Sum | |
---|---|---|---|
HP | 48 | 2 | 50 |
Small adenoma (LGD) | 3 | 2 | 5 |
Large adenoma (LGD) | 73 | 4 | 77 |
Adenoma (HGD) | 20 | 0 | 20 |
TSA | 125 | 5 | 130 |
SSA/P | 110 | 0 | 110 |
MSS CRC | 35 | 5 | 40 |
MSI-L CRC | 40 | 2 | 42 |
MSI-H CRC | 99 | 7 | 106 |
SUM | 159 | 15 | 174 |
Abbreviations: HP, hyperplastic polyps; LGD, low grade dysplasia; HGD, high grade dysplasia; TSA, traditional serrated adenoma; SSA/P, sessile serrated adenoma/polyp; CRC, colorectal cancer; MSS, microsatellite stable; MSI-L, low microsatellite instable; MSI-H, high microsatellite instable.