Table 3. Administration of study drug.
Weight | Standard FDC RHZE
(150/75/400/275 mg) |
Additional
Rifampicin 300mg caps / placebo |
Total R
dose in intervention arm |
Total R dose
in placebo arm |
Dose of other
TB drugs (H/Z/E) |
---|---|---|---|---|---|
30–37 kg | 2 tabs | 3 | 1200mg | 300mg | 150/800/550 |
38–54 kg | 3 tabs | 4 | 1650mg | 450mg | 225/1200/825 |
55–70 kg | 4 tabs | 1800mg | 600mg | 300/1600/1100 | |
≥ 71 kg | 5 tabs | 1950mg | 750mg | 375/2000/1375 |
R = rifampicin, H = isoniazid, Z = pyrazinamide, E = ethambutol.