Table 1. Baseline Patient Characteristics.
| Characteristic | No. of patients (%) | |
|---|---|---|
| RT (n = 63) | RT plus icotinib (n = 64) | |
| Age, y | ||
| ≤70-74 | 23 (36.5) | 29 (45.3) |
| ≥75-79 | 23 (36.5) | 22 (34.4) |
| ≥80 | 17 (27.0) | 13 (20.3) |
| Sex | ||
| Male | 36 (57.1) | 40 (62.5) |
| Female | 27 (42.9) | 24 (37.5) |
| ECOG performance status | ||
| 0-1 | 36 (57.1) | 31 (48.4) |
| 2 | 27 (42.9) | 33 (51.6) |
| T stage | ||
| T2 | 16 (25.4) | 17 (26.6) |
| T3 | 37 (58.7) | 35 (54.7) |
| T4 | 10 (15.9) | 12 (18.8) |
| N stage | ||
| N0 | 25 (39.7) | 27 (42.2) |
| N1 | 38 (60.3) | 37 (57.8) |
| M stage | ||
| M0 | 59 (93.7) | 61 (95.3) |
| M1a | 4 (6.3) | 3(4.7) |
| Clinical stage (UICC 2002) | ||
| IIA | 22 (34.9) | 21 (32.8) |
| IIB | 10 (15.9) | 12 (18.8) |
| III | 27(42.9) | 28 (43.8) |
| IVA | 4 (6.3) | 3 (4.7) |
| Tumor location | ||
| Cervical esophagus | 4 (6.3) | 6 (9.4) |
| Upper third | 17 (27.1) | 14 (21.9) |
| Middle third | 28 (44.4) | 31 (48.4) |
| Lower third | 14 (22.2) | 13 (20.3) |
| Tumor length, cm | ||
| <5 | 23 (36.5) | 31 (48.4) |
| ≥5 | 40 (63.5) | 33 (51.6) |
| Weight loss in 6 mo | ||
| ≤10% body weight | 22 (34.9) | 15 (23.4) |
| >10% body weight | 41 (65.1) | 49 (76.6) |
| Dysphagia, Atkinson scorea | ||
| 0-1 | 34 (54.0) | 37 (57.8) |
| ≥2 | 29 (46.0) | 27 (42.2) |
Abbreviations: ECOG, Eastern Cooperative Oncology; RT, radiation therapy.
a
Scores range from 0 to 4, with higher scores indicating greater dysphagia.