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. 2020 Oct 6;21:695. doi: 10.1186/s12864-020-07117-5

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Subcellular distribution of Chr 1 and Chr 2 in V. cholerae. Core genes are spatially enriched in the intracellular region near the old pole. Coloured core gene clusters (related to motility, peptidoglycan biosynthesis and ribosomal proteins) represent core gene products that co-localize with growth/survival-related reactions in the old pole of the cell. Two replication origins on Chr 1 indicate multifork replication. Active growth zones are indicated with blue dashed lines along the axis of the cell. Small dashes illustrate fast peptidoglycan growth and long dashes illustrate slower growth