Table 2.
Average values [along with standard deviation (SD), minimum, maximum and coefficient of variation (CV)] obtained for amyloid PET according to the processing method (N = 155).
| Region | Mean | SD | Min | Max | CV | (z-score difference) | 95% CI | OR | 95% CI | AUC | 95% CI | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Automatic Aβ-index | − 0.38 | 0.01 | − 0.40 | − 0.37 | − 3.04 | − 1.69 | − 1.96 | − 1.41 | 51.9 | 12.8 | 210.5 | 0.96 | 0.93 | 0.99 |
| Cerebellum gray matter | 1.24 | 0.02 | 1.22 | 1.27 | 1.72 | − 1.55 | − 1.85 | − 1.24 | 30.5 | 9.4 | 98.6 | 0.94 | 0.90 | 0.98 |
| Pons | 0.59 | 0.01 | 0.58 | 0.60 | 1.76 | − 0.90 | − 1.25 | − 0.55 | 2.7 | 1.8 | 4.1 | 0.74 | 0.65 | 0.82 |
| Whole cerebellum | 0.97 | 0.02 | 0.96 | 0.99 | 1.73 | − 1.53 | − 1.85 | − 1.20 | 19.5 | 7.1 | 53.3 | 0.92 | 0.87 | 0.97 |
| Whole cerebellum + brain stem | 0.88 | 0.02 | 0.87 | 0.90 | 1.74 | − 1.44 | − 1.77 | − 1.11 | 10.0 | 4.6 | 21.6 | 0.88 | 0.82 | 0.94 |
The discrimination between visually assessed amyloid positive and negative cases was assessed by the magnitude of separation computed as the difference between z-scores, the odds ratio (OR) computed by logistic regression and area under the ROC curves (AUC). All p values < 0.0001.