Table 2.
Immune cells densities and programmed death-ligand 1 (PD-L1) expression data by sample type and Fusobacterium nucleatum status from paired treated cohort.
| Sample type | Median (IQR) | P valuea |
Fusobacterium nucleatum status |
P valueb | ||
|---|---|---|---|---|---|---|
| Positive | Negative | |||||
| CD3+ | Pre Post |
1023.5 (745.8–1326.0) 669 (329.5–1301.8) |
0.12 | 1024.0 (760.0–1315.0) 261.0 (175.8–387.0) |
1024.0 (583.5–1451.8) 723.5 (147.0–1578.5) |
0.95 0.004 |
| CD8+ | Pre Post |
119.0 (70.0–167.0) 312.0 (183.0–726.0) |
<0.001 | 119.0 (70.0–154.0) 163.0 (73.0–220.0) |
114.5 (69.0–203.0) 486.0 (34.0–788.0) |
0.81 0.001 |
| PD-L1 | Pre Post |
14.3 (6.0–20.5) 3.9 (1.2–12.7) |
0.15 | 14.3 (5.5–20.5) 1.1 (0.7–3.5) |
13.9 (7.7–19.0) 5.9 (1.9–17.1) |
0.97 0.02 |
a
Wilcoxon test for paired samples.
b
Mann–Whitney U test for unpaired samples.