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. 2020 Oct 7;8(2):e001437. doi: 10.1136/jitc-2020-001437

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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CCIs in colon cancer with MSS and MSI. The directions and number of ligand–receptor interactions in MSS (A) and MSI (B) tumors in GSE146771. The intracellular network of PD1 in CD8⁺ T cells in MSS (C) and MSI (D) tumors. (E) The expression level of MHC-I molecules and MHC-II molecules (HLA-DRA) in MSI and MSS colon cancer in the TCGA colon cancer cohort. (F) The TCGA colon cancer transcriptome data were analyzed using the curated Molecular Signatures Database.