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. 2020 Oct 7;19:76. doi: 10.1186/s12938-020-00822-y

Table 4.

Applications of functional 3D models in treating cardiovascular diseases

Application Materials Purpose
Heart valve condition
 Aortic valve stenosis [71] TangoPlus, Verowhite In vitro assessment of stenosis severity
 Mitral valve stenosis [82] Mold star 15, Ecoflex 00–30 In vitro assessment of stenosis severity
 Mitral valve regurgitation [74] Mold star 15, Ecoflex 00–30 Surgical simulation: mitral valve repair, mitral-clip
 Artificial valve [84, 85] Silicone Device development: exploring relationships between artificial valve thickness and valve function
Coronary heart disease
 Coronary heart disease [87, 89] Wax, VeroClear Surgical planning: optimal stent placement; parameter evaluation criteria: FFR
Vascular disease
 Intracranial aneurysm [90] Semi-translucent PLA Surgical simulation: diverter implantation
 Abdominal aortic aneurysm [92] Polyjet Material Rubber FLX930 Surgical simulation: transcatheter intervention repair