Table 1. Percentage Inhibition of Egg Albumin Protein Denaturation by the Synthesized Compoundsa.
inhibition of protein denaturation (%) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
con (μg/mL) | std* | 5a* | 5b* | 5c* | 5d* | 5e* | 5f* | 5g* | 5h* | 5i* | 5j* | 5k* | 5l* |
20 | 42.98 ± 1.28 | 11.66 ± 0.95 | 22.66 ± 1.05 | 12.76 ± 0.99 | 24.46 ± 1.19 | 28.63 ± 0.68 | 17.65 ± 1.34 | 9.94 ± 0.53 | 19.18 ± 0.71 | 25.49 ± 0.85 | 30.66 ± 1.04 | 31.42 ± 0.95 | 32.63 ± 1.07 |
40 | 57.08 ± 1.6 | 20.51 ± 0.82 | 30.51 ± 2.22 | 22.51 ± 2.33 | 35.06 ± 0.56 | 39.23 ± 1.37 | 27.27 ± 1.52 | 16.82 ± 1.74 | 27.92 ± 1.59 | 31.18 ± 1.28 | 40.01 ± 1.33 | 41.00 ± 1.24 | 43.20 ± 1.87 |
60 | 75.54 ± 1.26 | 28.25 ± 1.47 | 42.86 ± 2.43 | 28.91 ± 1.44 | 48.94 ± 1.53 | 51.18 ± 1.26 | 35.26 ± 1.42 | 26.00 ± 1.00 | 37.33 ± 1.43 | 49.24 ± 1.60 | 53.98 ± 1.78 | 56.72 ± 2.00 | 59.51 ± 2.46 |
80 | 83.56 ± 0.96 | 39.55 ± 0.92 | 52.54 ± 0.90 | 39.65 ± 1.08 | 61.43 ± 1.24 | 65.57 ± 1.33 | 49.58 ± 0.98 | 37.61 ± 1.99 | 49.89 ± 1.45 | 58.12 ± 0.56 | 68.39 ± 1.00 | 71.47 ± 0.90 | 78.24 ± 1.37 |
100 | 94.60 ± 0.90 | 52.56 ± 0.80 | 69.65 ± 1.21 | 58.28 ± 1.29 | 73.82 ± 1.45 | 77.37 ± 0.94 | 62.06 ± 1.57 | 49.70 ± 0.73 | 65.78 ± 1.64 | 71.07 ± 0.34 | 80.34 ± 0.95 | 83.46 ± 2.21 | 87.97 ± 1.37 |
IC50 μg/mL | 35.03 | 95.11 | 76.12 | 85.79 | 61.29 | 58.62 | 80.68 | 100.60 | 80.18 | 62.74 | 55.58 | 52.89 | 46.29 |
Values are expressed as mean ± SD, n = 3, and * Correlation is significant at the 0.01 level.