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. 2020 Oct 7;39:209. doi: 10.1186/s13046-020-01702-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — The negative relationship of CRT and IRE1α expression in human PC samples was coordinately associated with the survival of PC patients. a, d Low CRT (a) and positive IRE1α (d) expression in normal pancreas. b, e High CRT (b) and negative IRE1α (e) expression in one serial PC sample. c, f Low CRT (c) and positive IRE1α (f) expression in another serial PC sample. g Kaplan–Meier curves for patients with high versus low CRT expression in tumors. h Kaplan–Meier curves for patients with positive (+) versus negative (−) IRE1α expression in tumors. I Kaplan–Meier curves for patients with the co-expression of CRT and IRE1α