Table 3.

Multivariable Cox regression analysis of predictors of MACE

	All patients N = 309	Patients without MACE N = 267	Patients with MACE N = 42	*P-value
CSBF at rest (mL/min)	92 ± 38	87 ± 34	121 ± 48	< 0.001
CSBF during ATP infusion (mL/min)	234 ± 81**	230 ± 81**	238 ± 84**	0.58
ΔCSBF (mL/min)	140 ± 67	143 ± 68	117 ± 53	0.016
Coronary flow reserve	2.7 ± 0.9	2.8 ± 0.9	2.0 ± 0.4	< 0.001
Coronary flow reserve < 2.0	55 (17%)	30 (11%)	25 (60%)	< 0.001

Data are expressed as mean ± standard deviation or number (%)

* P-values represent the difference between patients with and without MACE. ** P < 0.05 vs. CSBF at rest

ΔCSBF = CSBF during ATP infusion – CSBF at rest. Coronary flow reserve = CSBF during ATP infusion / CSBF at rest × 100

ATP adenosine triphosphate, CSBF coronary sinus blood flow, MACE major adverse cardiac events