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. 2020 Mar 23;26(11):1281–1297. doi: 10.1177/1352458520907901

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© The Author(s), 2020

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — (a) Forest plot demonstrating OR_MS for HLA⁺EBNA^hi persons. (b) Forest plot demonstrating OR_MS for HLA⁺EBNA^lo persons. (c) Forest plot demonstrating OR_MS for HLA^–EBNA^hi persons. (d) Bar chart demonstrating evidence of interaction between HLA-DRB1*1501 genotype and EBNA antibody titre on an additive, but not multiplicative scale. The dotted line represents the null (OR = 1). (e)–(h) Forest plots demonstrating estimates of interaction – AP, RERI, synergy index, and multiplicative interaction respectively – for studies with individual-level data available. The reference group (with OR = 1) is HLA^–EBNA^lo individuals for all panels. MIT: multiplicative interaction term.