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. 2019 Aug 2;26(11):1381–1391. doi: 10.1177/1352458519864933

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© The Author(s), 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Study design.

BL: baseline, EDSS: Expanded Disability Status Scale; FU: follow-up; MRI: magnetic resonance imaging; SC: spinal cord; 9-HPT: 9-hole peg test; 25-FWT: 25-foot walk test.

Figure 1 shows the study design. Patients were subdivided into four groups based on baseline MRI and subsequently separately analyzed based on new developed lesions after 2 years. The risk of EDSS progression and EDSS-plus progression after 6 and 11 years of follow-up was analyzed using logistic regression.