Table 2.
Spinal cord lesions | Baseline lesions |
New lesions after 2 years |
||||
---|---|---|---|---|---|---|
OR | 95% CI | p value | OR | 95% CI | p value | |
EDSS progression—Y6 | 3.6 | 1.42–9.03 | 0.007 | 1.09 | 0.50–2.40 | 0.82 |
EDSS-plus progression—Y6 | 2.5 | 1.10–5.47 | 0.028 | 1.18 | 0.53–2.60 | 0.69 |
EDSS progression—Y11 | 2.8 | 1.02–7.51 | 0.047 | 1.07 | 0.42–2.76 | 0.89 |
EDSS-plus progression—Y11 | 1.3 | 0.46–3.77 | 0.605 | 1.17 | 0.40–3.41 | 0.77 |
Infratentorial lesions | Baseline lesions |
New lesions after 2 years |
||||
OR | 95% CI | p value | OR | 95% CI | p value | |
EDSS progression—Y6 | 0.7 | 0.32–1.35 | 0.256 | 1.84 | 0.81–4.22 | 0.15 |
EDSS-plus progression—Y6 | 0.7 | 0.34–1.54 | 0.345 | 1.44 | 0.62–3.35 | 0.39 |
EDSS progression—Y11 | 0.4 | 0.18–1.07 | 0.069 | 1.61 | 0.58–4.45 | 0.67 |
EDSS-plus progression—Y11 | 0.7 | 0.26–1.72 | 0.400 | 1.58 | 0.48–5.21 | 0.46 |
CI: confidence interval; EDSS: Expanded Disability Status Scale; FU: follow-up; OR: odds ratio; Y: year.
Table 2 shows the risk (in odds ratios) to encounter the different outcome measures for patients with baseline spinal cord lesions compared to patients without spinal cord lesions (upper panel), and baseline infratentorial compared to no infratentorial lesions (lower panel).
All regression analyses were corrected for T2 supratentorial lesions at baseline and the use of disease-modifying treatment (DMT) until follow-up. Level of significance was set at p 0.05 (bold).