Table 4.
Treatment‐related adverse events
| Toxicity type | Grade 3–5, n (%) | Grade 3, n (%) | Grade 4, n (%) | Grade 5, n (%) |
|---|---|---|---|---|
| Hematologic | 103 (19) | 78 (14) | 24 (4) | 1 (1) |
| Neutropenia | 52 (10) | 49 (9) | 3 (1) | |
| Anemia | 39 (7) | 37 (6) | 2 (1) | |
| Thrombocytopenia | 24 (4) | 24 (4) | ||
| Febrile neutropenia | 8 (1) | 5 (1) | 1 (1) | 1 (1) |
| Nonhematologic | 151 (28) | 126 (23) | 24 (4) | 1 (1) |
| Fatigue | 76 (14) | 73 (13) | 3 (1) | |
| Diarrhea | 49 (9) | 40 (7) | 9 (2) | |
| Mucositis | 16 (3) | 16 (3) | ||
| Nausea/vomiting | 22 (4) | 22 (4) | ||
| Neuropathy | 36 (7) | 7 (1) | ||
| Dermatologic toxicity | 21 (4) | 4 (1) | ||
| Others | 48 (9) | 41 (7) | 7 (1) | 1 (1) |