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. 2020 Aug 28;25(10):878–885. doi: 10.1634/theoncologist.2020-0167

Table 1.

Patient characteristics

Characteristics n (%)
No. of patients 81
Age, median (range), yr 39 (21–78)
Male vs. female 41 vs. 40
Stage I–II 23 (28)
Stage III–IV 58 (72)
No. of therapies before CBT, median (range) 4 (1–11)
No. of SCTs prior to CBT 40 (49)
Auto 31
Allo 6
Both (with allo most recent) 3
Disease status prior to CBT
Relapsed (responded for more than 6 mo) 22
Refractory (progressed within 6 mo) 59
DOR to most recent treatment prior to CBT, median (range), days 84 (0–2,953)
No. of CBT infusions, median (range) 8 (1–41)
Best response to CBT
PD 17 (21)
SD 18 (22)
PR 38 (47)
CR 7 (9)
Indeterminate 1 (1)
Reason for discontinuing CBT
PD 53 (65)
Toxicity 13 (16)
Transplant prep 10 (12)
Infection 1
Per protocol 1
CR after adding chemo 1
CR to CBT but PD after discontinuation 2
DOR to post‐CBT therapy, median (range), days 169 (30–1,490)
Time between CBT and subsequent treatment, median (range), days 47 (0–737)
No. of SCTs after CBT 38 (47)
Auto 16
Allo 22

Abbreviations: Allo, allogeneic; Auto, autologous; CBT, checkpoint blockade; CR, complete response; DOR, duration of response; PD, progression of disease; PR, partial response; SCT, stem cell transplant; SD, stable disease.