Table 1.
Characteristics of the autopsy COVID-19 cases.
Case no. | Age/gender | Survival since symptom onset (days) | Hospitalization (days) | COVID-19 severity (at admission) | Clinical symptoms | Chest imaging | Past medical history | Clinical diagnoses of death causes and complications |
---|---|---|---|---|---|---|---|---|
1 | 73/Fa | 35 | 32 | Severe | Fever, cough, dyspnea | Bilateral patchy interstitial infiltrates | Hypertension, COPDc | 1. COVID-19 (Critical) |
2. MODSe (including ARDSd) | ||||||||
3. Secondary infection | ||||||||
4. Sepsis | ||||||||
5. Thrombosis | ||||||||
2 | 88/Mb | 20 | 15 | Critical | Fever, cough | Bilateral ground-glass changes | COPD, | 1. COVID-19 (Critical) |
low back pain | 2. ARDS | |||||||
3. Secondary infection | ||||||||
3 | 74/F | 30 | 6 | Severe | Fever, cough, dyspnea | Bilateral diffuse patchy interstitial infiltrates | Brain tumor | 1. COVID-19 (Critical) |
2. ARDS | ||||||||
3. Anemia | ||||||||
4. Secondary infection | ||||||||
4 | 64/M | 30 | 19 | Severe | Fever, cough, sputum production, dyspnea | Bilateral diffuse ground-glass changes | Tuberculosis, | 1. COVID-19 (Critical) |
hypertension | 2. ARDS | |||||||
5 | 56/F | 42 | 16 | Severe | Fever, cough, sputum production, dyspnea | Bilateral patchy interstitial infiltrates | Heart disease (unknown), | 1. COVID-19 (Critical) |
post-cholecystectomy | 2. MODS | |||||||
3. Acute kidney injury | ||||||||
4. Secondary infection | ||||||||
6 | 76/M | 29 | 4 | Critical | Fever, dyspnea | Patchy ground-glass changes in right lung | No notable past medical history | 1. COVID-19 (Critical) |
2. MODS (including ARDS) | ||||||||
3. Sepsis | ||||||||
4. Thrombosis | ||||||||
5. Secondary infection | ||||||||
7 | 72/M | 34 | 20 | Severe | Headache, anorexia | Bilateral patchy ground-glass changes | Hypertension, lacunar cerebral infarction | 1. COVID-19 (Critical) |
2. ARDS | ||||||||
3. Secondary infection | ||||||||
8 | 86/F | 23 | 18 | Severe | Fever, cough, sputum production, dyspnea | Bilateral patchy ground-glass changes | Hypertension, coronary heart disease, chronic renal insufficiency | 1. COVID-19 (Critical) |
2. MODS (including ARDS) | ||||||||
3. Secondary infection | ||||||||
9 | 62/M | 31 | 15 | Severe | Fever, cough, dyspnea | Ground-glass changes in lower lobes of both lungs | No notable past medical history | 1. COVID-19 (Critical) |
2. ARDS | ||||||||
3. Acute liver injury | ||||||||
4. Acute kidney injury | ||||||||
10 | 51/M | 28 | 6 | Critical | Fever, cough, sputum production, dyspnea | White lung | Hypertension, gout | 1. COVID-19 (Critical) |
2. ARDS | ||||||||
3. Sepsis | ||||||||
4. Cardiac insufficiency | ||||||||
5. Acute liver and kidney injuries | ||||||||
6. Secondary infection | ||||||||
11 | 78/M | 27 | 13 | Critical | Fever, dyspnea | Ground-glass changes in lower lobes of both lungs | Hypertension | 1. COVID-19 (Critical) |
2. MODS (including ARDS) | ||||||||
3. Sepsis | ||||||||
4. Secondary infection | ||||||||
12 | 67/F | 21 | 14 | Severe | Fever, dyspnea | Bilateral ground-glass changes | No notable past medical history | 1. COVID-19 (Critical) |
2. MODS (including ARDS) | ||||||||
3. Secondary infection |
aF, female; bM, male; cCOPD, chronic obstructive pulmonary disease; dARDS, acute respiratory distress syndrome; eMODS, multiple organ dysfunction syndrome.