Table 3. .
Prevalence Groupb | No. | Shifted Range (N1) | Shifted Totals (N1) | % Shifted (N1)c | Shifted Range (N3) | Shifted Totals (N3) | % Shifted (N3)c |
---|---|---|---|---|---|---|---|
1 | 820 | 37.0–40 | 22 | 2.7 [1.8–4.0] | 37.5–40 | 0 | 0.0 [0.0–0.69] |
2 | 1113 | 38.3–40 | 7 | 0.63 [0.3–1.3] | 38.7–40 | 0 | 0.0 [0.0–0.51] |
3 | 1158 | 37.6–40 | 17 | 1.5 [0.9–2.3] | 38.1–40 | 0 | 0.0 [0.0–0.49] |
All groups combined | 3091 | 46 | 1.5 [1.1–2.0] | 0 | 0.0 [0.0–0.18] |
Abbreviation: Ct, cycle threshold.
aThe shift in N1 and N3 Ct values for pooled testing was calculated from Passing-Bablok regression analysis of pooled and singlicate positive specimens. Shift = (40 – intercept)/slope. The number of single-positive specimens with Ct values in the range of 40 – shiftN1 and 40 – shiftN3 was then tabulated.
bSpecimens were drawn from 3 geographic prevalence groups, as described in the “Methods” section.
cShown as value [95% CI].