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. 2020 Sep 29;7(11):ofaa466. doi: 10.1093/ofid/ofaa466

Table 3. .

Percentage of Single-Positive Specimens With Ct Values Within the Shifted Rangea

Prevalence Groupb No. Shifted Range (N1) Shifted Totals (N1) % Shifted (N1)c Shifted Range (N3) Shifted Totals (N3) % Shifted (N3)c
1 820 37.0–40 22 2.7 [1.8–4.0] 37.5–40 0 0.0 [0.0–0.69]
2 1113 38.3–40 7 0.63 [0.3–1.3] 38.7–40 0 0.0 [0.0–0.51]
3 1158 37.6–40 17 1.5 [0.9–2.3] 38.1–40 0 0.0 [0.0–0.49]
All groups combined 3091 46 1.5 [1.1–2.0] 0 0.0 [0.0–0.18]

Abbreviation: Ct, cycle threshold.

aThe shift in N1 and N3 Ct values for pooled testing was calculated from Passing-Bablok regression analysis of pooled and singlicate positive specimens. Shift = (40 – intercept)/slope. The number of single-positive specimens with Ct values in the range of 40 – shiftN1 and 40 – shiftN3 was then tabulated.

bSpecimens were drawn from 3 geographic prevalence groups, as described in the “Methods” section.

cShown as value [95% CI].