Figure 3.

An example of a bimodal ADP distribution: PDB entry 4rqz. This protein has three domains. One of the domains makes contact with a single copy of its symmetry mate. This domain, together with its symmetry mate, has higher mobility than the rest of the molecule. (a) Gaussian mixture model for peak-height distribution. (b) The mixture of SIGDs. (c) Domains corresponding to the clusters in the ADP distribution. (d) Crystal contacts of the third domain of PDB entry 4rqz: an enlarged and rotated version of the region marked by an oval in (c).