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. Author manuscript; available in PMC: 2020 Oct 8.
Published in final edited form as: J Immunother. 2017 Sep;40(7):265–276. doi: 10.1097/CJI.0000000000000179

FIGURE 2.

FIGURE 2.

A, Phenotypes of peripheral blood natural killer cells subsets. Peripheral blood mononuclear cells were stained for CD56, CD16, granzyme A, gzm B, KIR2DL2, CD62, and CD69 and thereafter analyzed by flow cytometry. Expression of these molecules in relation to CD56 density on CD3−CD56 + NK cells is shown. B, Cytotoxicity of peripheral blood natural killer cells on the NB cell lines. Cytokine-activated NK cell did efficiently lyse NB cells, especially in the 10:1 ratio. The cytotoxicity achieved by treatment of interleukin 21 (10 ng/mL) (P < 0.05). NB indicates neuroblastoma; NK cell, natural killer cell.