Table 2.

Comparison of COVID-19 symptoms, hyposmia, and hypogeusia between hospitalized, hospital outpatients, and primary care outpatients

	Hospitalized patients N = 198	Hospital outpatients N = 129	Primary care outpatients N = 63	p value global	p value adjusted-hospitalized patients vs hospital outpatients	p value hospitalized patients vs primary care outpatients	p value hospital outpatient vs primary care outpatients
Time since onset of first symptom (days)	9 (5–12)	14 (10–19)	7 (4–10)	< 0.001	< 0.001	0.030	< 0.001
Asthenia	122 (62%)	108 (84%)	35 (56%)	< 0.001	< 0.001	0.46	< 0.001
Cough	151 (76%)	97 (75%)	51 (81%)	0.676
Fever	165 (83%)	92 (71%)	19 (30%)	< 0.001	0.013	< 0.001	< 0.001
Headache	31 (16%)	83 (64%)	34 (54%)	< 0.001	< 0.001	< 0.001	0.208
Diarrhea and/or vomiting	70 (35%)	42 (33%)	8 (13%)	0.003	0.635	0.001	0.004
Dyspnea	115 (58%)	34 (26%)	26 (41%)	< 0.001	< 0.001	0.032	0.046
Neurological manifestations	21 (11%)	10 (8%)	1 (2%)	0.056	0.44	0.1	0.156
Nasal obstruction	9 (5%)	37 (29%)	18 (29%)	< 0.001	< 0.001	< 0.001	1.00
Rhinorrhea	9 (5%)	53 (41%)	27 (43%)	< 0.001	< 0.001	< 0.001	0.877
Hyposmia	24 (12%)	84 (65%)	21 (33%)	< 0.001	< 0.001	< 0.001	< 0.001
Persistent hyposmia	22/24 (92%)	26/84 (31%)	19/21 (90%)	0.001	< 0.0001	0.225	0.003
Hyposmia without nasal obstruction nor rhinorrhea	23 (12%)	40 (31%)	11 (17%)	< 0.001	< 0.0001	0.282	0.084
Hypogeusia	26 (13%)	77 (60%)	27 (43%)	< 0.001	< 0.001	< 0.001	0.032
Persistent hypogeusia	22/26 (85%)	26/77 (34%)	22/27 (81%)	< 0.001	< 0.001	0.309	0.002

Data expressed in median (IQR) for continuous variables or N (%) for qualitative data