Table 3.

Comparison of demographics, comorbidities, symptoms, and severity criteria between patients with hyposmia and/or hypogeusia and patients without hyposmia nor hypogeusia

	Univariate analysis			Multivariate analysis
Variables	No hyposmia nor hypogeusia N = 237	Hyposmia and/or hypogeusia N = 153	p value	OR (95% CI)	p value
Age (years)	60 (47–75)	46.5 (33–56)	< 0.001	0.97 (0.96–0.99)	< 0.001
Female	104 (44%)	84 (55%)	0.038
HTA	79 (33%)	32 (21%)	0.011
Diabetes	45 (19%)	16 (10%)	0.032
Obesity	25 (11%)	12 (8%)	0.48
Bronchopathy	40 (17%)	12 (8%)	0.014	0.44 (0.21–0.94)	0.034
Cardiopathy	37 (16%)	8 (5%)	0.002
Nephropathy	17 (7%)	3 (2%)	0.032
Neurological diseases	25 (11%)	3 (2%)	0.001	0.27 (0.08–0.95)	0.042
Cancer	22 (9%)	4 (3%)	0.011
Hemopathy	14 (6%)	2 (1%)	0.034
Graft	7 (3%)	2 (1%)	0.49
Other immunodepression*	17 (7%)	7 (5%)	0.39
Time since onset of first symptom (days)	9 (5–13)	11 (8–15)	0.001
Asthenia	132 (56%)	133 (87%)	< 0.001	4.83 (2.7–8.65)	< 0.001
Cough	178 (75%)	121 (79%)	0.39
Fever	170 (72%)	106 (69%)
Headache	60 (25%)	88 (58%)	< 0.001	1.88 (1.11–3.19)	0.018
Diarrhea and/or vomiting	69 (29%)	51 (33%)	0.43
Dyspnea	119 (50%)	56 (37%)	0.009
Neurological manifestations	18 (8%)	14 (9%)	0.58
Signs of respiratory severity	101 (43%)	28 (18%)	< 0.001	0.51 (0.29–0.91)	0.023
Oxygen therapy ≥ 3 l	60 (25%)	15 (10%)	0.0002
Non-invasive ventilation	12 (5%)	0 (0%)	0.004
Invasive ventilation	8 (3%)	3 (2%)	0.54

^*HIV, autoimmune disease, inflammatory disease, sickle cell anemia. Data expressed in median (IQR) for continuous variables or N (%) for qualitative data