Skip to main content
. 2020 Oct 8;15(10):e0236606. doi: 10.1371/journal.pone.0236606

Fig 1. Locomotor effects of cannabidiol (CBD) at different concentrations.

Fig 1

After a 24-h withdrawal, CBD (10 μg/mL) induced significant reductions in locomotory activity (A). CBD (5 and 10 μg/mL) induced increases in locomotory activity compared with a dose of 0.5 μg/mL (B). Cnt: control, M: methanol. *P < 0.05, **P < 0.01 vs. control, #P < 0.05, ##P < 0.01 vs. drug treatment. Tukey’s multiple comparison test. All values are expressed as the mean ± SEM. In the graphs, the durations of movement are expressed as an absolute time (s). In term of percentages of the total assay time, times of 1000, 2000, and 3000 s correspond to 9.259%, 18.518%, and 27.777%, respectively. Each experiment; n = 96.