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. 2020 Sep 28;18(9):e3000870. doi: 10.1371/journal.pbio.3000870

Fig 6. Association of lipid species with menopausal status.

Fig 6

Multivariable linear regression analysis between menopausal status (post relative to pre) and log10-transformed lipid species concentrations was performed in women only, adjusting for age, BMI, smoking status, and diabetes status. Beta coefficients were converted to percentage difference of lipid level in postmenopausal relative to premenopausal women. Open circles show nonsignificant species (p > 0.05). Grey and pink closed circles show species with corrected p < 0.05 and corrected p < 2.5 × 10−7, respectively. See S1 Data for the underlying data. BMI, body mass index; CE, cholesteryl ester; Cer, ceramide; Cer-1-P, ceramide-1-phosphate; COH, free cholesterol; DE, dehydrocholesterol; deoxyCer, deoxyceramide; DG, diacylglycerol; dhCer, dihydroceramide; GM1, GM1 ganglioside; GM3, GM3 ganglioside; HexCer, monohexosylceramide; Hex2Cer, dihexosylceramide; Hex3Cer, trihexosylceramide; LPC, lysophosphatidylcholine; LPC(O), lysoalkylphosphatidylcholine; LPC(P), lysoalkenylphosphatidylcholine; LPE, lysophosphatidylethanolamine; LPE(P), lysoalkenylphosphatidylethanolamine; LPI, lysophosphatidylinositol; NL, neutral loss; PC, phosphatidylcholine; PC(O), alkylphosphatidycholine; PC(P), alkenylphosphatidylcholine; PE, phosphatidylethanolamine; PE(O), alkylphosphatidylethanolamine; PE(P), alkenylphosphatidylethanolamine; PG, phosphatidylgylcerol; PI, phosphatidylinositol; PS, phosphatidylserine; SIM, single ion monitoring; SM, sphingomyelin; sn, stereospecifically numbered; Sph, sphingosine; S-1-P, sphingosine-1-phosphate; TG, triacylglycerol; TG(O), alkyl-diacylglycerol.