Fig 4. Temporal expression profile of BmCoc throughout the life cycle.

Temporal expression profile of BmCoc was investigated throughout the life cycle from the stages of early embryo to the adult moth, and the silkworm ribosomal protein L3 (RpL3) was used as the internal reference. I144, I156, I168h: the time after incubation; 1^st 1d: day 1 of the first instar; 1^st m: the molting stage of the first instar; 2^nd 1d: day 1 of the second instar; 2^nd 2d: day 2 of the second instar; 2^nd m: the molting stage of the second instar; 3^rd 1d: day 1 of the third instar; 3^rd m: the molting stage of the third instar; 4^th 1d: day 1 of the fourth instar; 4^th m: the molting stage of the fourth instar; 5^th 1d: day 1 of the fifth instar; W0: the time the wandering stage was initiated; P1–P8: days 1–8 of pupae; M: moth.