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. 2020 Oct 8;11(10):e00241. doi: 10.14309/ctg.0000000000000241

Table 2.

Changes in primary and secondary outcomesa

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Variable Mean change from baseline (95% CI) Between-group difference (95% CI)
JX pill group (N = 70) Control group (N = 71) JX pill group vs control group P valueb
GISc
 Week 4 −5.5 (−4.8, −6.3) −4.2 (−3.5, −4.9) −1.3 (−2.4, −0.3) 0.013
 Week 8 −6.7 (−5.9, −7.4) −5.3 (−4.6, −6.1) −1.3 (−2.4, −0.2) 0.016
HAMDd
 Week 4 −4.9 (−4.2, −5.7) −4.2 (−3.4, −4.9) −0.7 (−1.8, −0.3) 0.093
 Week 8 −6.0 (−5.2, −6.7) −5.2 (−4.5, −5.9) −0.7 (−1.7, −0.2) 0.174
HAMAe
 Week 4 −3.9 (−3.2, −4.6) −3.6 (−2.9, −4.3) −0.3 (−1.3, −0.7) 0.446
 Week 8 −4.8 (−4.0, −5.6) −4.2 (−3.4, −4.9) −0.6 (−1.7, −0.5) 0.431

CI, confidence interval; FD, functional dyspepsia; GIS, Gastrointestinal Symptom Score; HAMA, Hamilton Anxiety Scale; HAMD, Hamilton Depression Scale; JX, Jiawei Xiaoyao.

a

All values are mean, with the 95% CIs.

b

P values were calculated based on a repeated-measures analysis of variance.

c

The severity of FD symptoms is assessed by the GIS. Scores range from 0 to 40, with higher scores indicating more severe symptoms.

d

The HAMD score separately evaluates the depression status of participants. Scores range from 0 to 54, with 0 equaling no depression.

e

The HAMA score separately evaluates the anxiety status of participants. Scores range from 0 to 56, with 0 equaling no anxiety.