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. 2020 Sep 17;48(18):10087–10100. doi: 10.1093/nar/gkaa737

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Crystal structures of RNA 10-mers carrying m⁴C and m⁴₂C modifications. (A) Superposition of the three determined structures presented only as backbone (cartoon, left) and nucleobases (sticks, right); (B) individual structures of RNA 10-mers CCGG(m⁴C)GCCGG (orange), CCGG(m⁴₂C)GCCGG crystallized in the P2₁2₁2₁ space group (cyan) and CCGG(m⁴₂C)GCCGG crystallized the R3₂ space group (violet) shown in the same orientation as in panel A.