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. 2020 Sep 29;48(18):10101–10124. doi: 10.1093/nar/gkaa750

Figure 9.

Figure 9.

HPLC analysis of degradation of oligonucleotides (0.1 mg/ml) 3′-terminally modified with (A) one or (B) two non-methylated guanosines or 5′-(R)- or 5′-(S)-C-methyl-guanosines in the presence of 75 mU/ml SVPD in 50 mM Tris (pH 7.2) and 10 mM MgCl2.