Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (i) 1) TMSCl/pyridine, 0°C to room temperature, 1 h. 2) isobutyrylchloride/pyridine, 0°C to room temperature, overnight; 93%. (ii) Dess–Martin periodinane/DCM, 0°C to room temperature, 2 h. (iii) MeMgBr/DCM, 0°C, 30 min; 2 steps 33% as a mixture of 3 and 13. (iv) TBDPSCl, imidazole/DMF, room temperature, overnight; 17% for 4 and 23% for 14.
