Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Half-lives of oligonucleotides modified at the 3′ termini with 5′-(R)- or 5′-(S)-C-methyl-guanosines in the presence of 75 mU/ml SVPD
| Oligonucleotide | t 1/2 (h) | Oligonucleotide | t 1/2 (h) |
|---|---|---|---|
| dT19POG | <1 | dT18GPOG | <1 |
| dT19POS | 70.7 | dT18SPOS | 260 |
| dT19POR | 7.1 | dT18RPOR | 20.8 |
| dT19PSG | 14.4 | dT18GPSG | 65.5 |
| dT19PSS | No degradation | dT18SPsS | No degradation |
| dT19PSR | 22.6 | dT18RPSR | 89 |
