Table 3.
Association between blood pressure single-nucleotide polymorphisms with components of blood pressure components and pulse wave velocity
| Augmentation pressure |
Blood pressure at P1 |
Pulse wave velocity |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| SBP ID | Gene | BP trait | beta | P | OLS | beta | P | OLS | beta | P | OLS |
| rs10923038 | DBP | −0.09 | <0.01 | −0.09 | — | — | — | — | — | — | |
| rs3742182 | DBP | 0.11 | <0.01 | 0.09 | — | — | — | — | — | — | |
| rs3184504 | SHB3 | DBP/SBP/PP | 0.08 | <0.05 | 0.06 | — | — | — | — | — | — |
| rs3745318 | KLF2 | DBP | 0.07 | <0.05 | 0.07 | — | — | — | — | — | — |
| rs10842991 | DBP | 0.09 | <0.05 | 0.08 | — | — | — | — | — | — | |
| rs1055144 | LOC100506236 | SBP | −0.1 | <0.05 | −0.11 | — | — | — | — | — | — |
| rs11909120 | N6AMT1 | DBP | — | — | — | −0.6 | <0.05 | −0.67 | — | — | — |
| rs4810332 | SBP | — | — | — | 0.55 | <0.05 | 0.55 | — | — | — | |
| rs9860290 | CMSS1 | PP | — | — | — | −0.52 | 0.05 | −0.58 | — | — | — |
| rs9888615 | FERMT2 | SBP | — | — | — | −0.59 | <0.05 | −0.54 | −0.17 | <0.05 | −0.16 |
| rs2390258 | DBP/SBPPP | — | — | — | 0.45 | 0.05 | 0.47 | 0.23 | 0.001 | 0.26 | |
| rs4553000 | UBAP1 | DBP/SBP/PP | — | — | — | — | — | — | −0.22 | 0.001 | −0.19 |
| rs4980515 | DBP | — | — | — | — | — | — | −0.21 | 0.001 | −0.23 | |
DBP, diastolic blood pressure; OLS, ordinary least squares; P1, pressure at the first systolic shoulder; PP, pulse pressure; SBP, systolic blood pressure.