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. 2020 Apr 16;41(35):3304–3310. doi: 10.1093/eurheartj/ehaa193

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© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Associations of genetically predicted lifetime smoking index with 14 cardiovascular diseases in UK Biobank. Odds ratios are expressed per one standard deviation increase of the lifetime smoking index. Estimates are from the multiplicative random-effects inverse variance-weighted method. CI, confidence interval; OR, odds ratio. The I ² statistic quantifies the amount of heterogeneity among estimates based on individual SNPs individual SNPs. ^aSignificant at the Bonferroni-corrected threshold of P < 3.6 × 10⁻³.