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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Hypertension. 2020 Aug 24;76(5):1506–1513. doi: 10.1161/HYPERTENSIONAHA.120.15654

Table 2.

Hazard ratios for heart failure* by pregnancy complications in the first birth.

Complications in the first birth Number of women Number of events / women-years at risk Age-adjusted models Fully adjusted models
Hazard ratio (95% confidence interval) Hazard ratio (95% confidence interval)
By hypertensive disorder of pregnancy status only
No HDP 475,269 499 / 5,883,782 Reference Reference
HDP§ 33,153 66 / 399,858 1.92 (1.49–2.48)** 1.83 (1.41–2.36)**
Gestational hypertension 8,827 15 / 114,919 1.38 (0.82–2.30) 1.41 (0.84–2.35)
Preeclampsia 24,326 51 / 284,939 2.17 (1.63–2.90)** 2.00 (1.50–2.68)**
By hypertensive disorder of pregnancy, small-for-gestational age delivery, and preterm delivery status
No HDP 475,269 499 / 5,883,782 Reference Reference
HDP alone§ 22,585 42 / 273,255 1.78 (1.30–2.44)** 1.72 (1.26–2.36)#
HDP with preterm and/or SGA delivery§ 10,568 24 / 126,603 2.22 (1.48–3.35)** 2.04 (1.35–3.08)#
Gestational hypertension alone 6,948 10 / 89,863 1.19 (0.63–2.22) 1.21 (0.65–2.27)
Gestational hypertension with SGA and/or preterm birth 1,879 5 / 25,056 2.02 (0.84–4.88) 2.06 (0.85–4.98)
Preeclampsia alone 15,637 32 / 183,393 2.11 (1.48–3.02)** 1.99 (1.39–2.84)**
Preeclampsia with SGA and/or preterm birth 8,689 19 / 101,547 2.28 (1.44–3.61)** 2.04 (1.28–3.23)#
*

Heart failure endpoint is a composite of heart-failure related hospitalization and heart failure-related death

Age-adjusted models are adjusted only for maternal age at the last birth

Fully adjusted models are adjusted for maternal birth year, maternal age at first birth, maternal age at last birth, chronic diabetes diagnosis prior to last birth, and final party

§

HDP includes both gestational hypertension and preeclampsia

||

P<0.05,

#

P<0.01,

**

P<0.001