| Category | Parameter | Comment | Value |
|---|---|---|---|
| Model | nflux | Total flux number | 19 |
| nbalance | Number of flux balance equations | 8 | |
| nconstrain | Number of flux constraints (not including free fluxes) | 3 | |
| nmid | Number of MID predictions | 6 | |
| ndim | Number of free fluxes | 2 | |
| Fmin | Minimal flux value | 1 | |
| Fmax | Maximal flux value | 500 | |
| Finput | Value of supplement glucose flux in source tissue | 35 | |
| Fcirc,glc | Value of glucose turnover flux | 150.9 | |
| Fcirc,lac | Value of lactate turnover flux | 374.4 | |
| Optimization | nopt_repeat | Repeat number to optimize the cost function | 10 |
| Lthreshold | Objective value threshold to accept the fitting result | 0.1 | |
| Sample | nlattice | Sample number for each free flux | 1000 |
| FTCA,min | Minimal TCA flux value | 2 | |
| Hypoxia correction | amix | Assumed mixture ratio for hypoxia correction | 20% |
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